Gene: Lyst

lysosomal trafficking regulator
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View data by physiological system
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased lymphocyte cell number Lysttm1b(EUCOMM)Wtsi HOM postnatal 1.40×10-05
increased fasted circulating glucose level Lysttm1b(EUCOMM)Wtsi HOM postnatal 3.52×10-05
decreased body length Lysttm1b(EUCOMM)Wtsi HOM postnatal 6.92×10-05
increased mean corpuscular volume Lysttm1b(EUCOMM)Wtsi HOM postnatal 2.17×10-05
abnormal iris morphology Lysttm1b(EUCOMM)Wtsi HOM postnatal 3.62×10-16
abnormal coat/hair pigmentation Lysttm1b(EUCOMM)Wtsi HOM postnatal 2.38×10-21

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Filtered by: all phenotypes


Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
14 Images
Gross Pathology and Tissue Collection
8 Images
Combined SHIRPA and Dysmorphology
17 Images
2 Images
Eye Morphology: Images Slit Lamp
11 Images

 Disease Models

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Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental dysplasia Lysttm1b(EUCOMM)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Lysttm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Lysttm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice